Paris-Saclay Spring 2025 - Innovation event returns on 20 May

Innovation Article published on 07 February 2025 , Updated on 29 April 2025

Come and meet Université Paris-Saclay at the Paris-Saclay Spring exhibition. The event will take place on 20 May on the Institut Polytechnique de Paris campus in Palaiseau (Essonne), and will bring together all the key players in innovation in the Paris-Saclay region, Europe's leading deeptech cluster.

Since 2018, all the key players in innovation, research, science and economic development in Paris-Saclay have come together once a year at Paris-Saclay Spring, to showcase the technological innovation and scientific excellence of this leading deeptech biocluster in Europe.
Université Paris-Saclay will be attending again this year, right at the heart of the show in the Paris-Saclay village, accompanied by numerous partners. There will also be innovation projects related to Université Paris-Saclay.
Université Paris-Saclay, France's leading university and one of the world's Top 20, is demonstrating, with all its laboratories and its student and scientific communities, how its major role in innovation is providing answers to the challenges of today and tomorrow.

DataIA Institute
The Institute for Artificial Intelligence (AI) Research at Université Paris-Saclay brings together over 800 researchers from 47 different laboratories to promote interdisciplinary research in AI and data science. The winner of the "AI Cluster" call for projects in 2024, DataIA will be presenting its AI research projects and its major role in innovation.

Design Spot
Unique in France, the Université Paris-Saclay design centre is a meeting place for research, innovation and design. It supports students, researchers and entrepreneurs in their projects. Through the three projects on show, Widy (technology for measuring temperatures using thermal noise), SOUND (acoustic technology that diffuses sound through vibrations) and Pyrat (software for verifying AI performance), Design Spot shows how design helps transform scientific innovations into practical, accessible solutions.


ENS Paris-Saclay
As a member school of Université Paris-Saclay, ENS Paris-Saclay will be present at the stand to showcase its research and innovation projects, in fields ranging from fundamental science to societal issues. 


EUGLOH
The European University Alliance for Global Health (EUGLOH), coordinated by Université Paris-Saclay, brings together nine leading European universities. They pool their expertise to meet today's societal challenges and provide a training programme of excellence combining high-quality teaching, research and cutting-edge facilities. The Alliance will be presenting its international goals in these areas.


Université Paris-Saclay Foundation
The Université Paris-Saclay Foundation promotes and supports the missions of Université Paris-Saclay through patronage and philanthropy, in terms of teaching, research, innovation and mediation.


INRAE
INRAE, a national research organisation and partner of Université Paris-Saclay, will be presenting The French Gut, which focuses on agriculture, food and the environment. This ambitious project aims to explore the role of the gut microbiota in human health, particularly in chronic disease. The project, led by INRAE's MetaGenoPolis centre, aims to raise public awareness of this issue and enrich its socio-economic collaborations.


Maison du doctorat
The Université Paris-Saclay Maison du doctorat supports the University's 4,500 PhD students in all disciplines. It will be presenting its support services with a focus on the deeptech entrepreneurship course, launched as part of the Université Paris-Saclay Innovation Alliance cluster (PUI in French), supported by Université Paris-Saclay.


UVSQ
As an associate member of Université Paris-Saclay, UVSQ will be presenting its nanosatellite space programme, led by the Laboratoire Atmosphères, Milieux, Observations Spatiales (LATMOS - Univ. Paris-Saclay/CNRS/Sorbonne Univ./UVSQ). This international satellite programme for research and education (INSPIRE) aims to study the Earth's radiation balance. Three satellites have already been launched, the latest in March 2025.
 

This year, a brand-new Corner Lab area will be set up at the show, highlighting innovative projects from research laboratories involved in the region's two university innovation clusters (PUI), including Université Paris-Saclay Innovation Alliance. The four PUI projects supported by Université Paris-Saclay will be present in this space:


Arrow, the result of collaboration between the Laboratoire Informatique, Bio-informatique, Systèmes Complexes (IBISC - Univ. Paris-Saclay/Univ. d'Évry) and the Ellen Poidatz Foundation, has developed the first active augmented reality walking rehabilitation video game. It is designed to improve the walking ability of children with neurological motor disabilities.


Cocapec, from the Institute of Physical Chemistry (ICP – Univ. Paris-Saclay/CNRS), is developing the stationary radiolytic synthesis of copper- and silver-based nanoparticles for applications in printed electronics.


Cyclope, from the Institut of Chemistry of Natural Substances (ICSN - Univ.Paris-Saclay/CNRS) and the the Infectious Processes in Tropical Island Environments unit (PIMIT - CNRS/Inserm/Institut de recherche pour le développement/Université de la Réunion)’ unit, is developing a video-endoscopic capsule with the special feature that it has to be swallowed. The camera then films its progress through the digestive tract. These elements are crucial for the early detection of colorectal cancer, among other things.

Probalidy, a project from the Inflammation, Microbiome and Immunosurveillance Laboratory (MI2 - Univ. Paris-Saclay, Inserm), and whose Microbiome in liver diseases: from susceptibility to treatment team has identified several bacteria in the gut microbiota that help to improve NASH-Non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD). These two diseases are the two largest malnutrition-related liver diseases in the world, for which there is no treatment.
 

Join Université Paris-Saclay at Spring to talk to the entities present and discover the innovative research and innovation projects on show!

SPRING 50: Start-ups related to Université Paris-Saclay will be at the event 

Chaque année, à l’occasion du salon Paris-Saclay Spring, l’écosystème du territoire Paris-Saclay distingue 50 start-up du territoire en les invitant à participer à l’événement dans le cadre de l’opération Spring 50.

Les 50 start-up sélectionnées dans le cadre de Spring 50 pour l’année 2025 bénéficieront de plusieurs avantages : un stand d’exposition au salon Paris-Saclay Spring, un workshop avec le parrain de cette édition Valérian Giesz, fondateur de la start-up à succès Quandela, des séances de coaching en communication et pitch, une couverture média… Certaines de ces start-up auront en outre la possibilité de pitcher sur la main stage du salon, le 20 mai.

Les start-up sélectionnées lors des précédentes éditions de Spring 50 ont entre-temps levé plus de 350 millions d’euros. Spring 50 représente donc une opportunité indéniable pour une start-up de se développer et de valoriser ses technologies!  

ArcSpace SAS: Co-founded by Adam Abdin, a CentraleSupélec alumnus who was awarded a PhD from Université Paris-Saclay in 2019, ArcSpace is developing a welding process for in-orbit use, for satellite assembly, repair and end-of-life management. The new in-orbit capabilities of ArcSpace tools, included in the in-orbit service missions of major space prime contractors, provide Europe's space industry with enhanced performance, sovereignty and competitiveness.


Ethylowheel: Co-founded by UVSQ alumna Julie Bruguière and Jaime Alonso, an alumnus of the Optical Institute Graduate School's channel for innovation and entrepreneurs (FIE), and supported by the Optical Institute Graduate School's 503 and IncubAlliance, Ethylowheel innovates in skin-contact alcohol detection for the automotive market.


Green Fusyon: Spearheaded by AgroParisTech alumnus Jacques de Montigny, this start-up is from Paris-Saclay Food and Bioproduct Engineering (SayFood - Univ. Paris-Saclay/AgroParisTech/INRAE) and the Process and Materials Engineering Laboratory (LGPM - Univ. Paris-Saclay/CentraleSupélec); under the name Green Fusyon it produces chlorella, a microalga rich in protein and omega-3 for the food industry. Its innovative process recovers nitrogenous water and CO₂ emissions from biogas, reducing its carbon footprint. By replacing conventional sources with sustainable ingredients, it improves the nutrition of products while reducing their environmental impact, thus meeting climate requirements and the Nutri-Score.


Hope Valley AI: Co-founded in April 2024 by Hakima Berdouz, a research engineer at the CEA, and stemming from research conducted at the Institute for Applied Sciences and Simulation for Low-Carbon Energies (ISAS - Univ. Paris-Saclay, CEA), Hope Valley AI is reinventing the future of non-ionising breast imaging by making it smarter, more effective, more accessible, more equitable and more user-friendly. The company is developing MAMMOPE, a modular, intelligent medical device for multimodal breast imaging, with the ambition of becoming the new gold standard for AI-assisted breast cancer screening by 2030.


Mycelium Technologies: Co-founded by two Université Paris-Saclay alumni, Laetitia Pierazzi and Jaafar Kilani. Mycelium Technologies is a French deeptech start-up specialising in the development of gourmet, nutritious foods based on mycelium - the hyphae or roots of mushrooms - providing a natural, sustainable alternative to meat. By using agricultural by-products to cultivate its mycelium, the company creates exceptionally nutritious foods, while respecting ecosystems thanks to its expertise, unique know-how and technological innovation.


NeoSense: Co-founded by CentraleSupélec alumni Florent Loete and Pierrick Legrand, NeoSense provides high-precision, non-contact, non-destructive sensors for measuring the quality of semiconductor materials and thin films.


Opack: Co-founded by CentraleSupélec alumnus William Peltier, Opack provides packages that can be reused 100 times, thanks to a patented inflatable cushioning system. Assembled in France, these packages reduce waste and optimise re-use logistics.


Revolty: Co-founded by UVSQ alumna Mathilde Janicot and CentraleSupélec alumnus Julen Urchoegia, Revolty creates affordable, environmentally-friendly residential solar storage solutions by reconditioning lithium-ion batteries from electric vehicles and backup power systems. It helps individuals reduce their electricity bills and become more energy self-sufficient.


SAFENAI: Founded by Julien Chiaroni, the former programme manager at the Systems and Technologies Integration Laboratory (List - Univ. Paris-Saclay/CEA), and Fabien Tschirhart, an alumnus of Université Évry Paris-Saclay, SAFENAI is tackling a major obstacle to the large-scale adoption of artificial intelligence (AI) in numerous sectors (industry, transport, etc.): the trust that users, whether citizens or companies, place in AI. With Klarity, the AI-dedicated governance and observability solution provided by the start-up, customers benefit from total visibility over the quality and risks of their AI, instantly detect problems in production and deploy them with confidence.


Scalnyx: Co-founded by Université Paris-Saclay alumnus and former CentraleSupélec lecturer Charly Bechara. SCALNYX is a French deeptech company specialszing in software development. It provides a No Code AI platform for the predictive analysis of financial data, based on causal artificial intelligence. The PROJECTOR platform enables the creation of business AI agents and learning on a wide range of user data to identify explicit causal links and hidden signals that can be used by experts for more informed and traceable decisions.


UNVEIL: Led by Jean-Jacques Greffet, Professor at the Charles Fabry Laboratory (LCF - Univ. Paris-Saclay/CNRS/Optical Institute Graduate School), and supported by Optical Institute Graduate School 503, IncubAlliance and CNRS Innovation, UNVEIL is developing a technology based on an exalted resonant cavity microscopy technique that detects individual nanoparticles without labelling. This will make it possible to measure their mass and concentration, detect aggregates and measure affinities.


V4CURE: In March 2023, Nicolas Gilles, a researcher at the CEA, and Sonia Escaich, the future CEO, set up the company V4Cure, a spin-off from the Experimental and Molecular Pharmacology Laboratory (LPEM) and the Molecular Engineering Department for Health (SIMOS), within the Medicines and Technologies for Health unit (MTS - Université Paris-Saclay, CEA, INRAE). The start-up's goal is to develop a drug candidate called V4C-232. This is a derivative of a toxin contained in the venom of the mamba, a sub-Saharan African snake whose bite is fatal to humans. This molecule could be used to treat two diseases - hyponatremia and polycystic kidney disease - which affect ten million people in the West.


Vikit: Co-founded by CentraleSupélec alumnus Jean-François Macresy, Vikit has created a Software Development Kit (SDK) that makes it quick and easy to create video generation agents using generative artificial intelligence. These agents use public and proprietary generative AI models in Vikit, while solving the problems of quality, reliability and relevance of the content generated - problems that today prevent the full use of video generative AI by businesses.


Volpil: Co-founded by CentraleSupélec alumni Thomas Houdbert and Rémi Fourault, Volpil is developing a fun, gamified mobile application that enables users to understand, optimise and add value to their electricity consumption. Volpil helps people take control of their consumption and become eco-responsible consumers who are remunerated by the electricity grid.

Join us on 20 May to discover the pitches of some of them on stage!