Physiologie et physiopathologie des rétrovirus endogènes et infectieux (RETRO-ENDO)

Laboratory presentation

The team of endogenous retroviruses and retroid elements of the higher eukaryotes works on human infectious and endogenous retroviruses. This laboratory has identified a domain that has immunosuppressive properties that play an essential role in the ability of these viruses to invade their host and in tumorigenesis role. Research also focuses on the ability of tumor cells to escape the antitumor immune response and penetration of the materno-fetal barrier of the mammalian placenta. This research activity, at the junction of virology, oncology, immunology and development, enables new vaccine and therapeutic approaches, taking into account the properties of the identified domains.