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Laboratoire Physiopathologie et pharmacologie clinique de la douleur (LPPD)

Laboratory presentation

The LPPCD focuses on the mechanisms of hyperalgesia and allodynia in humans, that is, on neurological phenomena involving exacerbated pathological pain. This research theme represents a major public health focus up to 30% of the total population. Located on the CHU Ambroise Paré site in Boulogne Billancourt, the unit has a clinical research vocation and works closely with a large number of patients with acute or chronic pathological pain. In addition, the unit's clinician network, coming from different Paris hospitals, offers a real wealth of samples and patients to coordinate major clinical trials in the field.

The 20 latest publications

Title Authors Publication date Source
How to treat chronic pain in rheumatic and musculoskeletal diseases (RMDs) – A pharmacological review Anne Priscille Trouvin 01/01/24 Joint Bone Spine
Paradoxical heat sensation as a manifestation of thermal hypesthesia: a study of 1090 patients with lesions of the somatosensory system Nadine Attal, Didier Bouhassira 01/01/24 Pain
Cross-perspectives on care pathways for painful osteoarthritis: A qualitative analysis in patients and healthcare professionals Serge Perrot 12/01/23 Musculoskeletal care
Chronic pain characteristics in COVID-19 survivors after an ICU stay. A cross-sectional study Valéria Martinez 12/01/23 Anaesthesia, Critical Care & Pain Medicine
Effectiveness of non-pharmacological interventions for fibromyalgia and quality of review methods: an overview of Cochrane Reviews Serge Perrot 12/01/23 Seminars in Arthritis and Rheumatism
Re-thinking the perception of long-term opioid use in RMDs Serge Perrot, Anne Priscille Trouvin 11/01/23 Nature Reviews Rheumatology
Pain in Parkinson disease: mechanistic substrates, main classification systems, and how to make sense out of them Didier Bouhassira 11/01/23 Pain
Personalized treatment of neuropathic pain: Where are we now? Didier Bouhassira, Nadine Attal 10/01/23 European Journal of Pain
Personalized pain management: Ready for it? Didier Bouhassira 10/01/23 European Journal of Pain
Reply to Andrassy and Mukhdomi Didier Bouhassira, Frederic Adam 09/01/23 Pain
Real-world data: How is paracetamol prescribed in low back pain and osteoarthritis in general practice in France? Serge Perrot 09/01/23 Douleur et Analgesie
Botulinum toxin A and neuropathic pain: An update Nadine Attal 08/15/23 Toxicon
Joint European Academy of Neurology–European Pain Federation–Neuropathic Pain Special Interest Group of the International Association for the Study of Pain guidelines on neuropathic pain assessment Nadine Attal, Didier Bouhassira 08/01/23 European Journal of Neurology
Advances and challenges in neuropathic pain: a narrative review and future directions Nadine Attal, Didier Bouhassira 07/01/23 British Journal of Anaesthesia
Three dimensions of pain in osteoarthritis: development and validation of the Osteoarthritis Symptom Inventory Scale Serge Perrot, Anne Priscille Trouvin, Didier Bouhassira 07/01/23 Pain
Pain in osteoarthritis from a symptom to a disease Serge Perrot, Trouvin Anne-Priscille 06/01/23 Best Practice and Research in Clinical Rheumatology
Diagnosing nociplastic pain in cancer survivors: a major step forward Nadine Attal 05/01/23 British Journal of Anaesthesia
Is fibromyalgia an immune-mediated disease? Anne Priscille Trouvin, Serge Perrot 05/01/23 Revue du Rhumatisme (Edition Francaise)
Diagnosis of neuropathic pain in polyneuropathy: should screening questionnaires be thrown out? Nadine Attal, Didier Bouhassira 05/01/23 Pain
Promoting inclusion, diversity and equity in pain science Didier Bouhassira 04/01/23 European Journal of Pain

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)