Institut Galien Paris-Saclay (IGPS)

Laboratory presentation

The Institut Galien Paris Sud (IGPS) is a major international player in nanomedicine research. His goal is to develop nanotechnologies to deliver drugs to target cell populations and modulate their effects or for in vitro diagnostics and in vivo. The unit enjoys excellent international visibility thanks to its numerous publications and communications. His innovative work on nanomedicine attracts many collaborations, as evidenced by registered patents and industrial contracts. It is divided into three main poles (Physical Chemistry, Galenic Pharmaceuticals, Analytics) around which 7 teams with complementary skills are concentrated. It is a member of LabEx Lermit and NanoSaclay as well as the Paris-Sud Institute of Therapeutic Innovation (IPSIT). The IGPS has numerous scientific facilities grouped into common services for some throughout the site, which are available to everyone. They allow an optimal collaboration between the different teams of the unit and also attract external teams.

The 20 latest publications

Title Authors Publication date Source
Coarse-Grained Model-Assisted Design of Polymer Prodrug Nanoparticles with Enhanced Cytotoxicity: A Combined Theoretical and Experimental Study Ping Gao, Julien Nicolas 03/18/24 Angewandte Chemie - International Edition
A review on hyphenation of droplet microfluidics to separation techniques: From instrumental conception to analytical applications for limited sample volumes Delaram Zohouri, Théo Lienard—Mayor, Sameh Obeid, Myriam Taverna, Thanh Duc Mai 02/22/24 Analytica Chimica Acta
Development of nanoparticles based on amphiphilic cyclodextrins for the delivery of active substances Christina Sizun 02/15/24 International Journal of Pharmaceutics
Controlled hydrogel-based encapsulation of macrophages determines cell survival and functionality upon cryopreservation Natalia A. Ortiz Silva, Stéphanie Denis, Juliette Vergnaud, H. Hillaireau 01/25/24 International Journal of Pharmaceutics
Leu-Enkephalin Lipid Prodrug Nanoparticles: Relationship between Nanoparticles’ Structure, Interaction with Bovine Serum Albumin, and Analgesic Activity Frédéric Gobeaux, Fabienne Testard 01/23/24 Chemistry of Materials
Low melting mixtures: Neoteric green solvents for flavor formulation François Xavier Legrand 01/15/24 Journal of Molecular Liquids
Understanding the interplay between surface properties and the aspect ratio of ellipsoidal nanomaterials Mickaël Bourge 01/05/24 Colloids and Surfaces A: Physicochemical and Engineering Aspects
Polyfluoroalkyl Chain-Based Assemblies for Biomimetic Catalysis Ping Gao, Julien Nicolas 01/02/24 Chemistry - A European Journal
Lipid and Transcriptional Regulation in a Parkinson's Disease Mouse Model by Intranasal Vesicular and Hexosomal Plasmalogen-Based Nanomedicines Yu Wu, Angelina Angelova 01/01/24 Advanced healthcare materials
Liposomal AntagomiR-155-5p Restores Anti-Inflammatory Macrophages and Improves Arthritis in Preclinical Models of Rheumatoid Arthritis Audrey Paoletti, Bineta Ly, Marie Péan de Ponfilly-Sotier, Juliette Pascaud, Elodie Rivière, Gaétane Nocturne, Xavier Mariette 01/01/24 Arthritis and Rheumatology
Infliximab aggregates produced in severe and mild elevated temperature stress conditions induce an extended specific CD4 T-cell response Victor Le-Minh, Baptiste Robin, Claire Smadja 01/01/24 European Journal of Pharmaceutical Sciences
Release of liposomes from hyaluronic acid-based hybrid systems: Effects of liposome surface and size Fabrice Cousin 12/15/23 International Journal of Pharmaceutics
A physiologically-based pharmacokinetic model for predicting doxorubicin disposition in multiple tissue levels and quantitative toxicity assessment Fang Ching Chao, Eloísa Berbel Manaia, Gilles Ponchel 12/01/23 Biomedicine and Pharmacotherapy
Nanoscale celecoxib prodrugs: As efficient anti-inflammatory principles Rudaba Saleem, Mujeeb ur Rehman 12/01/23 Journal of Drug Delivery Science and Technology
Nanotechnologies and controlled release formulations for the administration of bisphosphonates and their potential in radiation protection Francois Fay, Elias Fattal 12/01/23 Journal of Drug Delivery Science and Technology
X-ray reflectivity study of the heat shock protein Hsp70 interaction with an artificial cell membrane model Ali Makky 12/01/23 Scientific Reports
Volumetric and Simultaneous Photoacoustic and Ultrasound Imaging with a Conventional Linear Array in a Multiview Scanning Scheme Clément Linger 12/01/23 IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Human dendritic cell maturation induced by amorphous silica nanoparticles is Syk-dependent and triggered by lipid raft aggregation François Xavier Legrand 12/01/23 Particle and Fibre Toxicology
Exploring the permeability of Amphotericin B trough serum albumin dispersions and lipid nanocarriers for oral delivery Henrique Rodrigues Marcelino, Gilles Ponchel 11/05/23 International Journal of Pharmaceutics
Thermodynamic and structural properties of lipid-photosensitizer conjugates mixed with phospholipids: Impact on the formation and stability of nano-assemblies David Chapron, Jean Philippe Michel, Véronique Rosilio 11/01/23 Colloids and Surfaces B: Biointerfaces

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)