Institut de biologie intégrative de la cellule (I2BC)

Laboratory presentation

The Institute of Integrative Cell Biology (I2BC) brings together numerous research teams working on all aspects of the cell, from cell constituents to cell interaction. The institute is divided into five research departments. The first department (B3S) uses many techniques to study biological assemblages at different scales. The Cell Biology department uses numerous eukaryotic models to study the physiological functions of cells. The Department of Genome Biology focuses on the study of genetic material. The Microbiology department is interested in different organisms, such as bacteria, archaea and their viruses, both for their specificities and as models to study biological mechanisms. Finally, the Virology department studies host-virus interactions and processes involved in viral infections.

The 20 latest publications

Title Authors Publication date Source
A fatty acid anabolic pathway in specializedcells sustains a remote signal that controls egg activation in Drosophila Mickael Poidevin, Pierre Delamotte, Mae lle Devilliers, Perla Akiki, Delphine Petit, Cynthia Gillet, Jacques Montagne 03/14/24 PLoS Genetics
Ingested soil bacteria breach gut epithelia and prime systemic immunity in an insect P. Mergaert 03/12/24 Proceedings of the National Academy of Sciences of the United States of America
Direct evidence of lipid transport by the Drs2–Cdc50 flippase upon truncation of its terminal regions Thibaud Dieudonné, Cédric Montigny, Guillaume Lenoir 03/01/24 Protein Science
Immunomodulatory Effects of Histone Variant H2A.J in Ionizing Radiation Dermatitis Adèle Mangelinck, Carl Mann 03/01/24 International Journal of Radiation Oncology Biology Physics
Plant nucleoside N-ribohydrolases: riboside binding and role in nitrogen storage mobilization Armelle Vigouroux, Solange Moréra 03/01/24 Plant Journal
HYPK controls stability and catalytic activity of the N-terminal acetyltransferase A in Arabidopsis thaliana Jean Baptiste Boyer, Thierry Meinnel, Carmela Giglione 02/27/24 Cell Reports
An ascomycete H4 variant with an unknown function Claudio Scazzocchio 02/21/24 Royal Society Open Science
Disordered regions and folded modules in CAF-1 promote histone deposition in Schizosaccharomyces pombe Fouad Ouasti, Maxime Audin, Mehdi Tachekort, Elizabeth Cesard, Virginie Ropars, Paloma Fernández Varela, Gwenaelle Moal, Jessica Andreani, Raphaël Guerois, Francoise Ochsenbein 02/20/24 eLife
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion Jinmei Gao, Raphaël Guerois 02/15/24 Cell
Publisher Correction: Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis (Nature, (2023), 621, 7978, (415-422), 10.1038/s41586-023-06506-6) Simona Miron, Liza Boeffard-Dosierre, Rania Ghouil, Sophie Zinn-Justin 02/15/24 Nature
Activity of MukBEF for chromosome management in E. coli and its inhibition by MatP Mohammed Seba, Frederic Boccard, Stéphane Duigou 02/05/24 eLife
Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE Christophe Velours 02/01/24 Protein Science
CRISPR genotyping methods: Tracing the evolution from spoligotyping to machine learning P. Muzyukina, Olga Soutourina 02/01/24 Biochimie
Plastid terminal oxidase (PTOX) protects photosystem I and not photosystem II against photoinhibition in Arabidopsis thaliana and Marchantia polymorpha Marine Messant, Umama Hani, Thanh Lan Lai, Adjélé Wilson, Ginga Shimakawa, Anja Krieger-Liszkay 02/01/24 Plant Journal
Toxoplasma membrane inositol phospholipid binding protein TgREMIND is essential for secretory organelle function and host infection Rodrigue Houngue, Aissatou Dieng, Claire Boulogne, Stanislas Tomavo 01/23/24 Cell Reports
Second Coordination Sphere Effect Shifts CO<inf>2</inf> to CO Reduction by Iron Porphyrin from Fe<sup>0</sup> to Fe<sup>I</sup> Sk Amanullah, Philipp Gotico, Winfried Leibl, Manuel J. Llansola-Portoles, Tania Tibiletti, Annamaria Quaranta, Ally Aukauloo 01/22/24 Angewandte Chemie - International Edition
Integrin Facilitates the Internalization of TAT Peptide Conjugated to RGD Motif in Model Lipid Membranes Julien Pernier, Christophe Le Clainche 01/15/24 ChemBioChem
A Perspective on the Prospective Use of AI in Protein Structure Prediction Thibault Tubiana, Jessica Andreani 01/08/24 Journal of Chemical Information and Modeling
Understanding the interplay between surface properties and the aspect ratio of ellipsoidal nanomaterials Mickaël Bourge 01/05/24 Colloids and Surfaces A: Physicochemical and Engineering Aspects
Tuning of the Chl<inf>D1</inf> and Chl<inf>D2</inf> properties in photosystem II by site-directed mutagenesis of neighbouring amino acids Alain Boussac 01/01/24 Biochimica et Biophysica Acta - Bioenergetics

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)