Infection et inflammation (2I)

Laboratory presentation

The research laboratory for infection and chronic inflammation (2I) works on chronic inflammation, the immune system, the neuroendocrine response to sepsis or the pathophysiology and diagnosis of microbial infections. Research focuses more particularly on the first axis of rapidly growing mycobacteria infections in a context of respiratory disease (especially in patients with cystic fibrosis). The second line of research concerns coagulase-negative staphylococci and prosthetic infections. Finally, the last line of research concerns infections due to respiratory syncytial virus (RSV).

The 20 latest publications

Title Authors Publication date Source
Family studies: A useful tool to better understand spondyloarthritis Félicie Costantino, Maxime Breban 03/01/24 Revue du Rhumatisme (Edition Francaise)
The IL-4/13-induced production of M2 chemokines by human lung macrophages is enhanced by adenosine and PGE<inf>2</inf> Matthieu Glorion 02/15/24 International Immunopharmacology
Blood Monocyte Phenotype Is A Marker of Cardiovascular Risk in Type 2 Diabetes Hendrick Mambu Mambueni, Henri Jean Garchon 01/19/24 Circulation Research
Reply Maxime Breban 01/01/24 Arthritis and Rheumatology
A novel antibacterial compound decreases MRSA biofilm formation without the use of antibiotics in a murine model Azzam Saleh-Mghir 01/01/24 Journal of Orthopaedic Research
Lumacaftor/Ivacaftor Population Pharmacokinetics in Pediatric Patients with Cystic Fibrosis: A First Step Toward Personalized Therapy Emmanuelle Bardin 01/01/24 Clinical Pharmacokinetics
Early post-exposure and curative therapeutic strategies against COVID-19 B. Davido 01/01/24 Revue des Maladies Respiratoires
A benchmark study of data normalisation methods for PTR-TOF-MS exhaled breath metabolomics Elodie Lamy, Emmanuelle Bardin, Stanislas Grassin-Delyle 01/01/24 Journal of Breath Research
Effect of achieving bone sterilisation on bone architecture and bone marrow, in an experimental rabbit model of osteomyelitis caused by carbapenemase-producing Enterobacterales B. Davido, A. C. Crémieux, P. De Truchis, Azzam Saleh-Mghir 12/01/23 International Journal of Antimicrobial Agents
Valproic acid as adjuvant treatment for convulsive status epilepticus: a randomised clinical trial Jean Claude Alvarez 12/01/23 Critical Care
Use CBD or drive, do you have to choose? Jean Claude Alvarez 11/01/23 Therapie
Association between Dental Scores and Saliva Uremic Toxins Islam Amine Larabi, Jean Claude Alvarez 11/01/23 Toxins
Imaging in inflammatory arthritis: progress towards precision medicine Maria Antonietta D’Agostino 10/01/23 Nature Reviews Rheumatology
Family studies: A useful tool to better understand spondyloarthritis Félicie Costantino, Maxime Breban 09/01/23 Joint Bone Spine
Hardening of Respiratory Syncytial Virus Inclusion Bodies by Cyclopamine Proceeds through Perturbation of the Interactions of the M2-1 Protein with RNA and the P Protein Cédric Diot, Jennifer Risso-Ballester, Marie Anne Rameix-Welti 09/01/23 International Journal of Molecular Sciences
Identification of Symptom Phenotypes of Hand Osteoarthritis Using Hierarchical Clustering: Results From the DIGICOD Cohort Félicie Costantino 07/01/23 Arthritis Care and Research
Response to the Letter to the Editor Regarding: “Noninvasive Vagus Nerve Stimulation: A New Therapeutic Approach for Pharmacoresistant Restless Legs Syndrome” Eric Azabou 07/01/23 Neuromodulation
Low versus standard calorie and protein feeding in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3) Virginie Maxime 07/01/23 The Lancet Respiratory Medicine
ATP-citrate lyase controls endothelial gluco-lipogenic metabolism and vascular inflammation in sepsis-associated organ injury Djillali Annane 07/01/23 Cell Death and Disease
EULAR study group on 'MHC-I-opathy': identifying disease-overarching mechanisms across disciplines and borders Félicie Costantino, Simon Glatigny, Maxime Breban 07/01/23 Annals of the Rheumatic Diseases

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)