Génétique Animale et Biologie Intégrative (GABI)

Laboratory presentation

GABI's scientific orientations are aimed at understanding and exploiting the genetic variability of animals to analyze the construction of phenotypes, interactions with microbial ecosystems and the wider environment, in an agro-ecological transition context. Among his priorities:
- Refine the knowledge of animal genomes, epigenomes and microbiomes and their interactions.
- Study functions related to adaptation traits, health, welfare, reproduction, and trade-offs of these with production traits.
- Develop tools and methods to promote efficient and sustainable livestock farming
- Characterize and manage animal biodiversity, a source of adaptability for future generations.
Founding member of the Paris Saclay Animal Sciences Institute ( SAPS ), the GABI unit is organized into seven research teams and one platform team.
GABI develops its research with projects in collaboration with various academic partners, companies and organizations of animal sectors. The unit is labeled by the Institut Carnot ( France Future Elevage ) and coordinates the national infrastructure CRB-Anim.

The 20 latest publications

Title Authors Publication date Source
Short communication: Correlation of methane production, intensity, and yield with residual feed intake throughout lactation in Holstein cows S. Fresco, Didier Boichard, Rachel Lefebvre, S. Fritz, Pauline Martin 03/01/24 Animal
Cell specification and functional interactions in the pig blastocyst inferred from single-cell transcriptomics and uterine fluids proteomics Adrien Dufour, Denis Laloë, Hervé Acloque 03/01/24 Genomics
Epithelial-to-mesenchymal plasticity from development to disease: An introduction to the special issue Hervé Acloque 02/01/24 Genesis
Genetic parameters, trends, and inbreeding in a honeybee breeding program for royal jelly production and behavioral traits Tristan Kistler, Florence Phocas 02/01/24 Apidologie
Long-term exposure from perinatal life to food-grade TiO<inf>2</inf> alters intestinal homeostasis and predisposes to food allergy in young mice Jérôme Lecardonnel 02/01/24 Allergy: European Journal of Allergy and Clinical Immunology
Multi-omics data integration for the identification of biomarkers for bull fertility Valentin Costes, Eli Sellem, Aurélie Bonnet, Hélène Kiefer 02/01/24 PLoS ONE
The potential of floating macrophytes as feed and phytoremediation resources to improve the environmental performance of giant gourami production in Indonesia: A life cycle assessment Simon Pouil 01/30/24 Aquaculture
Strengths and limitations of reduced representation bisulfite sequencing (RRBS) in the perspective of DNA methylation analysis in fish: a case-study on rainbow trout spermatozoa Delphine Lallias 01/01/24 Fish Physiology and Biochemistry
Establishment of a cloning-free CRISPR/Cas9 protocol to generate large deletions in the bovine MDBK cell line Dominique Rocha 01/01/24 Journal of Applied Genetics
Discrimination of familiar and unfamiliar human voices is independent of prolonged human-animal interaction in domestic chicks Marie Hélène Pinard-van der Laan, Fanny Calenge, Alexandre Lecoeur 01/01/24 Applied Animal Behaviour Science
Molecular mechanisms underlying the structural diversity of rhamnose-rich cell wall polysaccharides in lactococci Christine Pechoux 01/01/24 Journal of Biological Chemistry
Research Note: Intestinal avian defensin 2 and robustness of chicks Fany Blanc 01/01/24 Poultry Science
A compendium of genetic regulatory effects across pig tissues Elisabetta Giuffra, Dominique Rocha, Mathieu Charles 01/01/24 Nature Genetics
Targeted mutation and inactivation of the kinesin light chain 3 protein-encoding gene have no impact on mouse fertility† Christelle Le Danvic 01/01/24 Biology of Reproduction
Understanding bovine embryo elongation: a transcriptomic study of trophoblastic vesicles Denis Laloë, Marie Noelle Rossignol 01/01/24 Frontiers in Physiology
Isogenic lines of rainbow trout (Oncorhynchus mykiss) as a tool to assess how growth and feeding behaviour are correlated to feed efficiency in fish Simon Pouil, Edwige Quillet, Delphine Lallias, Florence Phocas, Mathilde Dupont-Nivet 12/15/23 Aquaculture
A Bos taurus sequencing methods benchmark for assembly, haplotyping, and variant calling Mekki Boussaha, Cécile Grohs, Didier Boichard 12/01/23 Scientific data
Comparison of goat and cow milk-derived extracellular vesicle miRNomes Zuzana Krupova, Christine Pechoux, Claudia Bevilacqua, Patrice Martin 12/01/23 Scientific data
Analysis of the impact of DGAT1 p.M435L and p.K232A variants on pre-mRNA splicing in a full-length gene assay Nicolas Gaiani, Lorraine Bourgeois-Brunel, Dominique Rocha, Arnaud Boulling 12/01/23 Scientific Reports
Whole genome sequencing reveals signals of adaptive admixture in Creole cattle Mekki Boussaha 12/01/23 Scientific Reports

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)