Biomarqueurs en cancérologie et onco-hématologie (BECCOH)

Laboratory presentation

The research activities of the BECCOH laboratory concern clinical trials and the development of biomarkers, for patients with cutaneous, digestive or pulmonary cancers, or histocytoses. The laboratory's teams aim for strong cross-sections, particularly around the development and validation of predictive and prognostic biomarkers allowing an ever increasing specification of the therapeutic management of patients. The BECCOH laboratory has a histological and molecular pathology platform for the study of neoplasia, and is backed by a center of biological resources (CRB) certified by AFNOR to NF96-900 standard.

The 20 latest publications

Title Authors Publication date Source
Lung transplantation as a rescue option in childhood critical pulmonary Langerhans cell histiocytosis Zofia Helias-Rodzevicz, Jean François Emile 01/01/24 Pediatric Pulmonology
Persistent nivolumab-induced urticaria with vibratory and delayed-pressure angioedema Romain Salle, Charbel Skayem, C. Longvert, E. Funck-Brentano 01/01/24 Journal of Allergy and Clinical Immunology: In Practice
Detection of wildtype Merkel cell polyomavirus genomic sequence and VP1 transcription in a subset of Merkel cell carcinoma Astrid Blom 01/01/24 Histopathology
Treponema pallidum resistance to azithromycin in France: A nationwide retrospective study from 2010 to 2022 Romain Salle 01/01/24 Journal of the European Academy of Dermatology and Venereology
European consensus-based interdisciplinary guideline for diagnosis, treatment and prevention of actinic keratoses, epithelial UV-induced dysplasia and field cancerization on behalf of European Association of Dermato-Oncology, European Dermatology Forum, European Academy of Dermatology and Venereology and Union of Medical Specialists (Union Européenne des Médecins Spécialistes) P. Saiag 01/01/24 Journal of the European Academy of Dermatology and Venereology
European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma. Part 1: Diagnostics and prevention–Update 2023 P. Saiag 11/01/23 European Journal of Cancer
European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma: Part 2. Treatment–Update 2023 P. Saiag 11/01/23 European Journal of Cancer
Avelumab vs Standard Second-Line Chemotherapy in Patients with Metastatic Colorectal Cancer and Microsatellite Instability: A Randomized Clinical Trial Jean François Emile 10/19/23 JAMA oncology
Distinct Regulation of EZH2 and its Repressive H3K27me3 Mark in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma Astrid Blom, P. Saiag 10/01/23 Journal of Investigative Dermatology
Childhood-onset Erdheim-Chester disease in the molecular era: clinical phenotypes and long-term outcomes of 21 patients Jean Donadieu, Jean François Emile 09/28/23 Blood
Combined Nivolumab and Ipilimumab in Octogenarian and Nonagenarian Melanoma Patients Capucine Baldini 09/01/23 Cancers
Unlocking the Potential of Biomarkers for Immune Checkpoint Inhibitors in Cancer Therapy Paul Takam Kamga 09/01/23 Cancers
A suggested protocol for the endocrine postoperative management of patients undergoing pituitary surgery Marie Laure Raffin Sanson 08/01/23 Annales d'Endocrinologie
PU.1 is a useful nuclear marker to distinguish between histiocytosis and histiocyte-rich tumours Irena Antonia Ungureanu, Jean Donadieu, Jean François Emile 08/01/23 Histopathology
Atopic dermatitis: A nationwide study on healthcare pathways and patient satisfaction of disease management in France Charbel Skayem, Romain Salle 08/01/23 Journal of the European Academy of Dermatology and Venereology
H syndrome mimicking Erdheim Chester disease: new entity and therapeutic perspectives Jean François Emile 08/01/23 Haematologica
Prevalence, patterns and outcomes of cardiac involvement in Erdheim-Chester disease Jean François Emile 07/07/23 European Heart Journal
Molecular and clinicopathologic characterization of pediatric histiocytoses Zofia Hélias-Rodzewicz, Nathalie Terrones, Rim Ben Jannet, Mariama Bakari, Jean François Emile 07/01/23 American Journal of Hematology
OCT2 expression in histiocytoses Irena Antonia Ungureanu, Zofia Hélias-Rodzewicz, Jean Donadieu, Jean François Emile 07/01/23 Virchows Archiv
A nationwide French cohort study on 3154 patients with atopic dermatitis and psoriasis to assess patients' perception of dermatology residents A. Faugeroux, Romain Salle, Charbel Skayem 07/01/23 Journal of the European Academy of Dermatology and Venereology

Number of publications of the laboratory by scientific field (2016-2021)

Every paper can be classified in one or more scientific fields. The figure below shows the lab's number of publications in each scientific field, according to the ASJC classification (Elsevier)